Long Term Clinical Prognostic Factors in Relapsing-Remitting Multiple Sclerosis: Insights from a 10-Year Observational Study.

Gabriel BstehRainer EhlingAndreas LutterottiHarald HegenFranziska Di PauliMichael AuerFlorian DeisenhammerMarkus ReindlThomas Berger
Published in: PloS one (2016)
We were able to identify clinically apparent chronic depression and cognitive dysfunction to be associated with adverse long term outcome in MS and to confirm that pregnancy has no negative impact. Additionally, we emphasize the positive predictive value of complete remission of initial symptoms.