LncRNA NEAT2 regulates oral squamous cell carcinoma progression via VEGFB and TGF-β/Smad3 pathway.

Published in: Oral diseases (2023)

NEAT2 downregulation inhibited cell proliferation and EMT through VEGFB and TGF-β/Smad3 pathway in vitro, disclosing a new regulatory mechanism in OSCC. In addition, downregulation of NEAT2 could inhibit the tumor growth and metastasis.

Keyphrases

transforming growth factor
cell proliferation
epithelial mesenchymal transition
signaling pathway
cell cycle
transcription factor
long non coding rna