Neutrophil-lymphocyte ratio reflects tumour-infiltrating lymphocytes and tumour-associated macrophages and independently predicts poor outcome in breast cancers with neoadjuvant chemotherapy.
Joshua J X LiShelly Y B NiJulia Y S TsangWai Yin ChanRay K W HungJoshua W H LuiSally W Y NgLeong Kwong ShumYing Fei TangGary M K TsePublished in: Histopathology (2024)
The association between NLR with tumour necrosis, TAMs and TILs illustrates an interaction between the circulating and local immune microenvironment. Late NLR is a strong indicator of outcome and may be useful for prognostication and disease monitoring.