Reduced plasma calcitonin gene-related peptide level identified in cluster headache: A prospective and controlled study.

Anja Sofie Petersen Nunu Lt Lund Karl MesslingerSarah Louise ChristensenMads BarloeseNiklas Rye JørgensenLisette J A KogelmanRigmor Højland Jensen

Published in: Cephalalgia : an international journal of headache (2024)

Plasma CGRP is unsuitable as a diagnostic biomarker of cluster headache or its disease states. The identified reduced CGRP levels suggest that CGRPs role in cluster headache is highly complex and future investigations are needed into the modulation of CGRP and its receptors.

Keyphrases

copy number
gene expression
dna methylation