Inhibition of visfatin alleviates sepsis-induced intestinal damage by inhibiting Hippo signaling pathway.

Zhong-Shen KuangYu-Xin LengNing YangZheng-Qian LiYa-Nan ZongDeng-Yang HanYue LiJin-Dan HeXing-Ning MiZhu-Kai CongXi ZhuChang-Yi WuXiang-Yang Guo

Published in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2022)

In short, this study demonstrated that inhibition of Visfatin might alleviate sepsis-induced intestinal injury through Hippo signaling pathway, supporting a further research on Visfatin as a therapeutic target.

Keyphrases

signaling pathway
high glucose
diabetic rats
pi k akt
intensive care unit
epithelial mesenchymal transition
septic shock
oxidative stress
induced apoptosis
endothelial cells
mouse model
cell proliferation