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Zika virus and its implications on cord blood banking and transplantation.

Elizabeth F StoneBeth H Shaz
Published in: Transfusion (2020)
Umbilical cord blood is an important cellular therapy product used for hematopoietic stem cell transplantation, but the US Food and Drug Administration guidance regarding donor screening to reduce the risk of Zika transmission has decreased the number of licensed, eligible cord blood units available for transplantation. There is a crucial need for updated travel risk assessment for Zika virus transmission, validated screening tests for Zika virus in umbilical cord blood, and further research on Zika virus transmissibility due to umbilical cord blood products to ensure that umbilical cord blood and related tissues are safe and available for transplantation.
Keyphrases
  • zika virus
  • umbilical cord
  • mesenchymal stem cells
  • cord blood
  • dengue virus
  • aedes aegypti
  • cell therapy
  • risk assessment
  • drug administration
  • stem cells
  • human health
  • smoking cessation
  • climate change