Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients.
Michael J JoynerR Scott WrightDeLisa FairweatherJonathon W SenefeldKatelyn A BrunoStephen A KlassenRickey E CarterAllan KlompasChad C WigginsJohn Ra ShepherdRobert ReaEmily WhelanAndrew ClayburnMatthew SpiegelPatrick JohnsonElizabeth R LesserSarah BakerKathryn F LarsonJuan Ripoll SanzKylie AndersenDavid HodgeKatie KunzeMatthew R BurasMatthew VogtVitaly HerasevichJoshua DennisRiley RegimbalPhilippe R BauerJanis BlairCamille van BuskirkJeffrey Lawrence WintersJames StubbsNigel PanethArturo CasadevallPublished in: medRxiv : the preprint server for health sciences (2020)
Given the deadly nature of COVID-19 and the large population of critically-ill patients included in these analyses, the mortality rate does not appear excessive. These early indicators suggest that transfusion of convalescent plasma is safe in hospitalized patients with COVID-19.