Pf bacteriophages hinder sputum antibiotic diffusion via electrostatic binding.

Qingquan ChenPam CaiTony Hong Wei ChangElizabeth BurgenerMichael J KratochvilAditi GuptaAviv HargilPatrick R SecorJosefine Eilsø NielsenAnnelise E BarronCarlos MillaSarah C HeilshornAndy SpakowitzPaul L Bollyky

Published in: bioRxiv : the preprint server for biology (2024)

Pf phages and sputum polymers reduce antibiotic diffusion via electrostatic interactions and liquid crystal formation.

Keyphrases

cystic fibrosis
mycobacterium tuberculosis
pulmonary tuberculosis
molecular dynamics simulations