Brain metastases in resected non-small cell lung cancer: The impact of different tyrosine kinase inhibitors.
Po-Jen YunGuan-Chyuan WangYing-Yi ChenTi-Hui WuHsu-Kai HuangShih-Chun LeeHung ChangTsai-Wang HuangPublished in: PloS one (2019)
EGFR-TKIs were effective in treating NSCLC patients with BM after curative pulmonary surgery, especially in those patients harboring EGFR mutations. Furthermore, the second-/third-generation EGFR-TKIs showed more promising results than the first-generation EGFR-TKIs in treating those particular patients, though larger studies needed to further prove the results.