An integrated package for bisulfite DNA methylation data analysis with Indel-sensitive mapping.

Qiangwei ZhouJing-Quan LimWing-Kin SungGuo Liang Li

Published in: BMC bioinformatics (2019)

BatMeth2 improves DNA methylation calling, particularly for regions close to indels. It is an autorun package and easy to use. In addition, a DNA methylation visualization program and a differential analysis program are provided in BatMeth2. We believe that BatMeth2 will facilitate the study of the mechanisms of DNA methylation in development and disease. BatMeth2 is an open source software program and is available on GitHub ( https://github.com/GuoliangLi-HZAU/BatMeth2 /).

Keyphrases

dna methylation
data analysis
genome wide
gene expression
quality improvement
copy number
high resolution
mass spectrometry