Genome-wide scan for runs of homozygosity identifies potential candidate genes associated with local adaptation in Valle del Belice sheep.

Salvatore MastrangeloMarco ToloneMaria T SardinaGianluca SottileAnna M SuteraRosalia Di GerlandoBaldassare Portolano

Published in: Genetics, selection, evolution : GSE (2017)

These results suggest that natural selection has, at least partially, a role in shaping the genome of Valle del Belice sheep and that ROH in the ovine genome may help to detect genomic regions involved in the determinism of traits under selection.

Keyphrases

genome wide
copy number
dna methylation
computed tomography
gene expression
human health
magnetic resonance imaging
risk assessment
climate change