The synergistic effect between adult weight changes and CYP24A1 polymorphisms is associated with pre- and postmenopausal breast cancer risk.

Shang CaoFeiran WeiJinyi ZhouZheng ZhuWei LiMing Wu

Published in: Breast cancer research and treatment (2019)

Significant interactions of weight change with CYP24A1 polymorphisms suggest CYP24A1 as a potential link between weight change and BC risk and the possibility that the impact of adult weight gain on postmenopausal BC risk may be enhanced by homozygous alleles of CYP24A1 SNPs.

Keyphrases

weight gain
breast cancer risk
body mass index
birth weight
weight loss
physical activity
bone mineral density
body weight
young adults
genome wide association