Interleukin-17 Promotes the Infiltration of CD8+ T Cells into the Brain in a Mouse Model for Alzheimer's Disease.
Xiaoyang YeJu ChenJie PanQi WuYue WangMengqian LuChengrong ZhangZhenzhen ZhangMuyan MaJinyong ZhuAnthony T VellaJun WanKepeng WangPublished in: Immunological investigations (2022)
Our data show that IL-17 signaling promotes neuroinflammation in AD by accelerating the infiltration of CD8+ T lymphocytes and Gr1+ CD11b+ myeloid cells.
Keyphrases
- mouse model
- induced apoptosis
- cell cycle arrest
- cerebral ischemia
- traumatic brain injury
- acute myeloid leukemia
- white matter
- electronic health record
- cognitive decline
- lipopolysaccharide induced
- resting state
- cognitive impairment
- lps induced
- endoplasmic reticulum stress
- inflammatory response
- signaling pathway
- oxidative stress
- immune response
- multiple sclerosis
- blood brain barrier
- subarachnoid hemorrhage
- pi k akt