Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties.

Nando D DasJen-Chien ChangChung-Chau HonS Thomas KellyShinsuke ItoMarina LizioBogumil KaczkowskiHisami WatanabeKeisuke KatsushimaAtsushi NatsumeHaruhiko KosekiYutaka KondoAki MinodaTakashi Umehara

Published in: BMC genomics (2023)

Collectively, our data highlights H4K5acK8ac's utility for identifying genes regulating cell-type specificity.

Keyphrases

genome wide
electronic health record
dna methylation
transcription factor
big data
genome wide identification
bioinformatics analysis
histone deacetylase
structural basis
machine learning
genome wide analysis