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Effects of xenogeneic transplantation of umbilical cord-derived mesenchymal stem cells combined with irbesartan on renal podocyte damage in diabetic rats.

Jing MengXiao GaoXiaojuan LiuWen ZhengYang WangYinghao WangZhenquan SunXiaoxing YinXueyan Zhou
Published in: Stem cell research & therapy (2024)
Compared to the administration of MSCs or irbesartan alone, the combination of MSCs and irbesartan exerted better protective effects on glomerular podocyte injury, providing new ideas for the clinical application of mesenchymal stem cells.
Keyphrases
  • umbilical cord
  • mesenchymal stem cells
  • diabetic rats
  • diabetic nephropathy
  • oxidative stress
  • high glucose
  • cell therapy
  • bone marrow
  • endothelial cells