Suppression of interleukin-6 increases enterovirus A71 lethality in mice.
Li-Chiu WangHui-Wen YaoChuan-Fa ChangShainn-Wei WangShih-Min WangShun-Hua ChenPublished in: Journal of biomedical science (2017)
Endogenous IL-6 functions to clear virus and protect the host from EV-A71 infection. Our study raises caution over the use of anti-IL-6 antibody or pentoxifylline to reduce IL-6 for patient treatment.