HIV Coinfection Predicts Failure of Ledipasvir/Sofosbuvir in Treatment-Naïve Noncirrhotic Patients With HCV Genotype 1.
Juan BerenguerJosé Luis CallejaMaría Luisa MontesÁngela GilAna MorenoRafael BañaresTeresa Aldámiz-EchevarríaAgustín AlbillosMaría Jesús TéllezAntonio OlveiraLourdes DomínguezInmaculada FernándezJavier García-SamaniegoBenjamín A PoloBeatriz ÁlvarezPablo RyanJosé BarrioMaría J DevesaLaura BenítezIgnacio SantosLuisa García BueyJosé SanzElvira PovesJuan E LosaConrado Fernández-RodríguezInmaculada JarrínMaría J CalvoJuan González-GarcíaPublished in: Open forum infectious diseases (2019)
The results of this large prospective study analyzing outcomes for LDV/SOF against HCV G1 in treatment-naïve noncirrhotic patients suggest that HIV infection is a predictor of treatment failure in patients with chronic hepatitis C.