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Early discontinuation of combination antibiotic therapy in severe community-acquired pneumonia: a retrospective cohort study.

Pauline GuillotFlora DelamaireArnaud GacouinBenoit PainvinCaroline PiauFlorian ReizineMathieu LesouhaitierJean-Marc TadiéAdel Maamar
Published in: BMC infectious diseases (2023)
Legionella pneumophila UAT proved to be highly effective in detecting the majority of cases, with only a negligible percentage of patients being missed, but is not sufficient to diagnose atypical pneumonia, and culture did not provide any supplementary information. These results suggest that the discontinuation of macrolides or quinolones may be a safe option when Legionella UAT is negative in countries with a low incidence of Legionella pneumonia.
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