Advanced diffusion imaging reveals microstructural characteristics of primary CNS lymphoma, allowing differentiation from glioblastoma.

Urs WürtembergerMartin DieboldAlexander RauVeysel AkgünLucas BeckerJürgen BeckPeter C ReinacherChristian A TaschnerMarco ReisertLuca FehrenbacherDaniel ErnyFlorian SchererMarc HohenhausHorst UrbachTheo Demerath

Published in: Neuro-oncology advances (2024)

Advanced diffusion imaging enables the characterization of the microstructure of PCNSL and reliably distinguishes PCNSL from GBM. Both imaging and histopathology revealed a relatively increased cell density and a preserved axonal microstructure in PCNSL.

Keyphrases

high resolution
white matter
single cell
spinal cord injury
diffuse large b cell lymphoma
stem cells
multiple sclerosis
photodynamic therapy
optic nerve