Interobserver agreement on definition of the target volume in stereotactic radiotherapy for pancreatic adenocarcinoma using different imaging modalities.
Eleni GkikaD KostyszynT FechterC MoustakisF ErnstJ Boda-HeggemannG SarriaK DieckmannS DobiaschM N DumaF EberleK KroegerB HäusslerV IzaguirreD JazmatiS LautenschlägerF LohausF MantelJ MenzelS PachmannM PavicK RadlanskiO RiestererS GerumF RöderJ WillnerS BarczykD ImhoffO BlanckA WittigM GuckenbergerAnca-L GrosuT B BrunnerPublished in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2023)
Overall, there was good GTV agreement (DSC). Combined metrics appeared to allow a more valid detection of interobserver variation. For SBRT, either 4D PET/CT or 3D PET/CT in treatment position with abdominal compression leads to better agreement and should be considered as a very useful imaging modality for the definition of treatment volumes in pancreatic SBRT. Contouring does not appear to be the weakest link in the treatment planning chain of SBRT for PACA.