Scop3D: Online Visualization of Mutation Rates on Protein Structure.

Lukasz KreftDemet TuranNiels HulstaertAlexander BotzkiLennart Martens Elien Vandermarliere

Published in: Journal of proteome research (2018)

Scop3D is a tool that automatically annotates protein structure with sequence conservation starting from a set of protein sequence variants. We present a complete upgrade and rewrite of Scop3D. We have included a DNA module that allows the analysis of single nucleotide polymorphisms in relation to the structural context of the protein. Scop3D therefore forms a bridge between genomics and protein structure. Moreover, Scop3D is now also available through an intuitive web-interface that makes the tool highly user-friendly.

Keyphrases

amino acid
protein protein
binding protein
small molecule
health information
low cost