The role of systolic-diastolic coupling in distinguishing impaired diastolic recoil in healthy aging and heart failure with preserved ejection fraction.
James P MacNamaraVivek KoshtiI-Jou ChengKatrin A DiasChristopher M HearonWilliam CornwellErin J HowdenBenjamin D LevineSatyam SarmaPublished in: Echocardiography (Mount Kisco, N.Y.) (2021)
Systolic-diastolic coupling, quantified by the EDexc /Sexc ratio, declined linearly with healthy aging. The EDexc /Sexc ratio was further reduced in HFpEF and able to predict HFpEF more accurately than e' alone. Systolic-diastolic coupling may be a useful diagnostic tool to detect HFpEF.