Adult neurogenic process in the subventricular zone-olfactory bulb system is regulated by Tau protein under prolonged stress.

Chrysoula DioliPatrícia PatrícioLucilia-Goreti PintoClemence MarieMónica MoraisSheela VyasJoão M BessaLuisa Pinto Ioannis Sotiropoulos

Published in: Cell proliferation (2021)

Our findings suggest the critical involvement of Tau in the neurogenesis suppression of SVZ and OB neurogenic niche under stressful conditions highlighting the role of Tau protein as an essential regulator of stress-driven plasticity deficits.

Keyphrases

cerebrospinal fluid
spinal cord injury
protein protein
traumatic brain injury
amino acid
stress induced
binding protein
transcription factor
small molecule
cerebral ischemia