Vitamin D Deficiency in Rats Causes Cardiac Dysfunction by Inducing Myocardial Insulin Resistance.
Hina Lateef NizamiParmeshwar KatarePankaj PrabhakarYashwant KumarSudheer Kumar AravaPraloy ChakrabortySubir Kumar MaulikSanjay Kumar BanerjeePublished in: Molecular nutrition & food research (2019)
Vitamin D deficiency in rats mimic high-fat-, high-fructose-induced metabolic syndrome and cardiac dysfunction. This study demonstrates that vitamin D deficiency is an independent risk factor for heart failure, at least in part, through induction of myocardial insulin resistance.
Keyphrases
- insulin resistance
- left ventricular
- metabolic syndrome
- heart failure
- adipose tissue
- high fat diet
- polycystic ovary syndrome
- skeletal muscle
- type diabetes
- oxidative stress
- cardiac resynchronization therapy
- high fat diet induced
- uric acid
- high glucose
- drug induced
- cardiovascular disease
- atrial fibrillation
- glycemic control