Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation.
Olaf M GlueckXiaoling LiangIrina BadellPaul R WratilAlexander GrafStefan KrebsHelmut BlumJohannes Christian HellmuthClemens SchererAlexandra HollausPatricia M SpaethBurak KarakocThimo FuchsJulia ZimmermannTeresa KaukeAndreas MoosmannOliver T KepplerChristian SchneiderMaximilian MuenchhoffPublished in: Infection (2023)
Patients in the early phase following lung allograft transplantation are vulnerable to infection with SARS-CoV-2 due to impaired immune responses. This patient population should be vaccinated before LuTx, protected from infection post-LuTx, and in case of infection treated generously with currently available interventions.