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Global metabolomic profiling reveals hepatic biosignatures that reflect the unique metabolic needs of late-term mother and fetus.

Nipun SainiManjot VirdeeKaylee K HelfrichSze Ting Cecilia KwanSusan M Smith
Published in: Metabolomics : Official journal of the Metabolomic Society (2021)
The metabolite profile of the late-term mouse dam and fetus is consistent with prior, non-rodent analyses utilizing plasma and urine. These data position mouse as a suitable model for mechanistic investigation into how maternal-fetal metabolism adapts (or not) to gestational stressors.
Keyphrases
  • birth weight
  • gestational age
  • preterm infants
  • weight gain
  • pregnancy outcomes
  • pregnant women
  • electronic health record
  • single cell
  • big data
  • preterm birth
  • body mass index