Hypoxia in solid tumors: a key promoter of cancer stem cell (CSC) resistance.
Masoud NajafiBagher FarhoodKeywan MortezaeeEbrahim KharazinejadJamal MajidpoorReza AhadiPublished in: Journal of cancer research and clinical oncology (2019)
Hypoxia, in fact, serves as a multi-tasking strategy to nurture CSCs with this adaptive capacity, complexing targeted therapies.