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Prognostic Impact of Different Gleason Patterns on Biopsy Within Grade Group 4 Prostate Cancer.

Keiichiro MoriVidit SharmaEva M ComperatShun SatoEkaterina LaukhtinaVictor M SchuettfortBenjamin PradereReza Sari MotlaghHadi MostafaeiFahad QuhalMehdi Kardoust PariziMohammad AbufarajPierre I KarakiewiczShin EgawaDerya TilkiStephen A BoorjianShahrokh F Shariat
Published in: Annals of surgical oncology (2021)
Patients with GG 4 at biopsy exhibited some limited biological and clinical heterogeneity. Specifically, GS 5 + 3 had an increased risk of GS upgrading. This can help individualize patients' counseling and encourage further study to refine biopsy specimen-based GG classification.
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