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Artemether and aspterric acid induce pancreatic α cells to transdifferentiate into β cells in zebrafish.

Jianxin JiaQi KangShunzhi LiuYabin SongF Susan WongYingkun QiuMing-Yu Li
Published in: British journal of pharmacology (2021)
Our data suggest that in zebrafish and αTC1-6 cells, both artemether and aspterric acid induce α cell transdifferentiation. Our data, along with those of Li et al. (2017), suggested that artemether and aspterric acid were able to induce α cell transdifferentiation, at least in zebrafish and αTC1-6 cells.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • single cell
  • stem cells
  • oxidative stress
  • cell death
  • signaling pathway
  • electronic health record
  • big data
  • cell proliferation
  • artificial intelligence