Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier.

Lesya KobylinskaI IvasechkoN SkorokhydR PanchukA RiabtsevaN MitinaA ZaichenkoR LesykB ZimenkovskyR StoikaS G Vari

Published in: Nanoscale research letters (2019)

Complexation of 4-thiazolidinone derivatives with a PEG-containing polymeric nanocarrier provided them with water solubility and enhanced pro-apoptotic effects in rat glioma C6 cells.

Keyphrases

drug delivery
cancer therapy
drug release
induced apoptosis
cell cycle arrest
cell death
anti inflammatory
oxidative stress
signaling pathway
pi k akt