Click-tambjamines as efficient and tunable bioactive anion transporters.
Israel Carreira-BarralMarcin MielczarekDaniel Alonso-CarrilloValeria CapurroVanessa Soto-CerratoRicardo Pérez TomásEmanuela CaciMaría García-ValverdeRoberto QuesadaPublished in: Chemical communications (Cambridge, England) (2020)
A novel class of transmembrane anion carriers, the click-tambjamines, display remarkable anionophoric activities in model liposomes and living cells. The versatility of this building block for the generation of molecular diversity offers promise to develop future drugs based on this design.