Optimization of percutaneous biopsy for diagnosis and pretreatment risk assessment of neuroblastoma.

Richard E OvermanTanvi T KartalAaron J CunninghamElizabeth A FialkowskiBindi J Naik-MathuriaSanjeev A VasudevanMarcus M MalekRanjeet KalsiHau D LeLinda Cherney StaffordTimothy B LautzBenjamin T ManyRachel E JonesAndreana BütterJacob DavidsonAndrew WilliamsRoshni DasguptaJana LewisMisty TrouttJennifer H Aldrink Sara A Mansfield Dave R LalJerry XiaoRebecka L MeyersScott S ShortErika A Newman

Published in: Pediatric blood & cancer (2020)

PCNB is a less invasive alternative to open biopsy for primary diagnosis and MYCN oncogene status in patients with neuroblastoma. Our data suggest that PCNB could be optimized for complete genetic analysis by standardized protocols and real-time pathology assessment of specimen quality.

Keyphrases

ultrasound guided
risk assessment
minimally invasive
electronic health record
human health
big data
machine learning
quality improvement