The role of Müller cells in tractional macular disorders: an optical coherence tomography study and physical model of mechanical force transmission.

Andrea GovettoJean-Pierre HubschmanDavid SarrafMarta S FigueroaFerdinando BottoniRoberto dell'OmoChristine A CurcioPatrizio SeidenariGiulia DelledonneRobert C GunzenhauserMariantonia FerraraAdrian AuGianni VirgiliAntonio ScialdoneRodolfo RepettoMario R Romano

Published in: The British journal of ophthalmology (2019)

Parafoveal Müller cells in the Henle fibre layer may guarantee structural stability of the parafovea by increasing retinal compliance and resistance to mechanical stress. Small values of the angle θ were related to worse BCVA possibly due to damage to Müller cell processes and photoreceptor's axons.

Keyphrases

optical coherence tomography
induced apoptosis
diabetic retinopathy
cell cycle arrest
oxidative stress
endoplasmic reticulum stress
physical activity
single cell
cell therapy
cell proliferation
optic nerve
stress induced
age related macular degeneration