PAM50 intrinsic subtypes, risk of recurrence score and breast cancer survival in HIV-positive and HIV-negative patients-a South African cohort study.
Boitumelo PhakathiTherese Dix-PeekEunice Van Den BergCaroline DickensSarah NietzHerbert CubaschMaureen JoffeAlfred I NeugutJudith S JacobsonPaul RuffRaquel DuartePublished in: Breast cancer research and treatment (2023)
Aggressive tumour biology was common in our cohort. HIV infection, PAM50 HER2-enriched,basal-like intrinsic subtypes and high ROR score were associated with poor overall and disease-free survival. HIV infection impacted survival in patients with luminal subtypes only.
Keyphrases
- free survival
- hiv positive
- antiretroviral therapy
- hiv infected
- men who have sex with men
- human immunodeficiency virus
- hiv aids
- end stage renal disease
- south africa
- hiv testing
- chronic kidney disease
- newly diagnosed
- peritoneal dialysis
- ejection fraction
- prognostic factors
- hepatitis c virus
- patient reported outcomes
- patient reported