CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics.
Anna JeppssonCarsten WikkelsöKaj BlennowHenrik ZetterbergRadu ConstantinescuAnne M RemesSanna-Kaisa HerukkaTuomas RauramaaKatarina NaggaVille LeinonenMats TullbergPublished in: Journal of neurology, neurosurgery, and psychiatry (2019)
The combination of the CSF biomarkers T-tau, Aβ40 and MCP-1 separates iNPH from cognitive and movement disorders with good diagnostic sensitivity and specificity. This may have important implications for diagnosis and clinical research on disease mechanisms for iNPH.