Nemonoxacin dosage adjustment in patients with severe renal impairment based on population pharmacokinetic and pharmacodynamic analysis.
Yi LiJianda LuYue KangXiaoyong XuXin LiYuancheng ChenKun WangXiaofen LiuYaxin FanHailan WuYu WangJiali HuJicheng YuJufang WuBeining GuoYingyuan ZhangXin ZengMing ZhaoJun XueJing ZhangPublished in: British journal of clinical pharmacology (2021)
An extended dosing interval (0.5 g q48h) may be appropriate for optimal efficacy of nemonoxacin in case of severe renal impairment.
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