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Intracranial aneurysms in patients with autosomal dominant polycystic kidney disease: prevalence, risk of rupture, and management. A systematic review.

Federico CagnazzoCarlo GambaccianiRiccardo MorgantiPaolo Perrini
Published in: Acta neurochirurgica (2017)
The prevalence of unruptured intracranial aneurysms in the ADPKD population is approximately 11%. Given the non-negligible rate of procedural complications, the management of these patients must be cautious and individualised. The rupture rate appears comparable to that of the general population. On the other hand, the 1.4% rate per patient-year of de novo aneurysms is non-negligible. These findings should be considered when counselling ADPKD patients regarding the appropriate management of intracranial aneurysms.
Keyphrases
  • end stage renal disease
  • polycystic kidney disease
  • ejection fraction
  • chronic kidney disease
  • newly diagnosed
  • risk factors
  • peritoneal dialysis
  • prognostic factors
  • hiv infected