Initiating chemotherapy in joint arthroplasty patients increases the risk of periprosthetic joint infections.

Amir Human Hoveidaei Amirhossein Ghaseminejad-RaeiniSeyed Hossein Hosseini-AslAshesh ShresthaArmin Hoveidaei Seyed Pouya TaghaviBasilia Onyinyechukwu NwankwoMohammad Saeid KhonjiJanet D Conway

Published in: Archives of orthopaedic and trauma surgery (2024)

This study reveals a possible relationship between postoperative chemotherapy and an increased incidence of PJI in patients with arthroplasty. Chemotherapy suppresses the immune system, rendering patients more vulnerable to infections. Additional research is required to confirm these findings.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
locally advanced
squamous cell carcinoma
radiation therapy
risk factors