Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis.
Jessica P RoelandsManon van der PloegMarieke E IjsselsteijnHao DangJurjen J BoonstraJames C H HardwickLukas J A C HawinkelsHans MorreauNoel F C C de MirandaPublished in: Gut (2022)
Spatial profiling revealed the molecular and immunological landscape of CRC tumourigenesis at early disease stage. We identified biomarkers with strong association with disease progression as well as targetable immune processes that are exploitable in a clinical setting.
Keyphrases