Complete Genome Sequence of Klebsiella pneumoniae Strain TK421, a Conjugative Hypervirulent Isolate.
Travis J KochanEgon Anderson OzerNathan B PincusMargaret A FitzpatrickAlan R HauserPublished in: Microbiology resource announcements (2020)
Klebsiella pneumoniae is a Gram-negative bacterium that is a major cause of nosocomial infections worldwide. Here, we present the complete genome sequence of TK421, a clinical bacteremia isolate containing a hypervirulence plasmid carrying tra-associated conjugation machinery genes. Emergence of conjugative hypervirulence plasmids could portend rapid dissemination of hypervirulence among multidrug-resistant K. pneumoniae strains.
Keyphrases
- klebsiella pneumoniae
- multidrug resistant
- gram negative
- escherichia coli
- acinetobacter baumannii
- drug resistant
- antibiotic resistance genes
- genome wide
- crispr cas
- gene expression
- genome wide identification
- loop mediated isothermal amplification
- respiratory tract
- transcription factor
- pseudomonas aeruginosa
- quantum dots
- genome wide analysis
- anaerobic digestion