Dual role of endoplasmic reticulum stress-ATF-6 activation in autophagy and apoptosis induced by cyclic stretch in myoblast.

Qiang ZhangGuirong LiuRan LiuJun LiuXuemin ZengDapeng RenXiao YanXiao Yuan

Published in: Apoptosis : an international journal on programmed cell death (2023)

ATF-6 pathway was activated in myoblast by mechanical stretch. ATF-6 may regulate the process of stretch-induced myoblast apoptosis and autophagy via CHOP, Bcl-2 and Beclin1 signaling.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
high glucose
diffuse large b cell lymphoma
diabetic rats
oxidative stress
transcription factor
signaling pathway
cell cycle arrest