Preoperative aspirin use and acute kidney injury after cardiac surgery: A propensity-score matched observational study.
Min HurChang-Hoon KooHyung-Chul LeeSun-Kyung ParkMinkyung KimWon Ho KimJin-Tae KimJae-Hyon BahkPublished in: PloS one (2017)
Preoperative low dose aspirin administration without discontinuation was protective against postoperative AKI defined by KDIGO criteria independently in both entire and matched cohort. Preoperative aspirin was also associated with decreased hemodialysis requirements and decreased postoperative hospital stay without increasing bleeding. However, differences in AKI and hospital stay were not associated with in-hospital mortality.
Keyphrases
- low dose
- acute kidney injury
- patients undergoing
- cardiac surgery
- high dose
- cardiovascular events
- healthcare
- antiplatelet therapy
- acute care
- adverse drug
- chronic kidney disease
- end stage renal disease
- atrial fibrillation
- emergency department
- peritoneal dialysis
- type diabetes
- coronary artery disease
- electronic health record