Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus.
Roldan M de GuiaAnna S HassingLouise J SkovCecilia RatnerKaja PlucińskaSøren MadsenThi A DiepGelo V Dela CruzSamuel A J TrammellElahu G SustarsicBrice EmanuelliMatthew P GillumZach Gerhart-HinesBirgitte HolstJonas T TreebakPublished in: Acta physiologica (Oxford, England) (2020)
Our findings indicate that regulation of NAMPT levels in hypothalamic neurons is important for the control of fasting- and ghrelin-induced food intake.