[Role of the intestinal MALT in pathogenesis of the IgA-nephropathy].
S V GulyaevL A StrizhakovNatalia V ChebotarevaSergey V MoiseevPublished in: Terapevticheskii arkhiv (2021)
Modern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or abnormal intestinal permeability are discussed in details. Based on supposed entero-renal pathogenesis of the disease future treatment modalities are considered. Relevant worlds literature is cited.