Stiffness-mediated mesenchymal stem cell fate decision in 3D-bioprinted hydrogels.

Yufan LiuZhao LiJianjun LiSiming YangYijie ZhangBin YaoWei SongXiaobing FuSha Huang

Published in: Burns & trauma (2020)

These results demonstrate that the differentiation of MSCs in 3D-bioprinted matrices is dependent on hydrogel stiffness, which emphasizes the importance of biophysical cues as a determinant of cellular behaviour.

Keyphrases

mesenchymal stem cells
drug delivery
hyaluronic acid
umbilical cord
tissue engineering
wound healing
bone marrow
drug release
decision making
cell therapy
extracellular matrix