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Cerebral Microbleeds and Treatment Effect of Intravenous Thrombolysis in Acute Stroke: An Analysis of the WAKE-UP Randomized Clinical Trial.

Ludwig SchlemmTim Bastian BraemswigFlorent BoutitieJan VynckierMärit JensenIvana GalinovicClaus Z SimonsenBastian ChengTae-Hee ChoFiehler JensJosep PuigVincent N ThijsJochen B FiebachKeith W MuirNorbert NighoghossianMartin EbingerSalvador PedrazaGötz ThomallaChristian GerloffMatthias EndresRobin LemmensChristian H Noltenull null
Published in: Neurology (2021)
This study provides Class II evidence that for patients with acute ischemic stroke with unknown time of onset and DWI-FLAIR mismatch who received IV alteplase, CMBs are not significantly associated with functional outcome at 90 days.
Keyphrases
  • acute ischemic stroke
  • high dose
  • diffusion weighted imaging
  • magnetic resonance
  • computed tomography
  • low dose
  • cerebral ischemia
  • replacement therapy