Is systems pharmacology ready to impact upon therapy development? A study on the cholesterol biosynthesis pathway.
Helen E BensonSteven WattersonJoanna L SharmanChido P MpamhangaAndrew PartonChristopher SouthanAnthony J HarmarPeter GhazalPublished in: British journal of pharmacology (2017)
We suggest solutions that facilitate systems pharmacology studies, based on the introduction of standards for data capture that increase the power of experimental data. We propose a systems pharmacology workflow for the refinement of data and the generation of future therapeutic hypotheses.