Targeted Regulation of Osteoblasts and Osteoclasts in Osteosarcoma Patients by CSF3R Receptor Inhibition of Osteolysis Caused by Tumor Inflammation Based on Transcriptional Spectrum Analysis and Drug Library Screening.

Qian LiJinlu ShanWei DuanYu Chen

Published in: Recent patents on anti-cancer drug discovery (2023)

CSF3R participates in the occurrence and development of OS bone destruction by regulating the inflammatory response of osteoblasts and osteoclasts and can affect the survival prognosis of OS patients.

Keyphrases

end stage renal disease
inflammatory response
newly diagnosed
chronic kidney disease
ejection fraction
prognostic factors
peritoneal dialysis
oxidative stress
risk assessment
bone loss
toll like receptor
lipopolysaccharide induced
body composition
patient reported
heat shock protein
heat shock
adverse drug