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Nickel-Catalyzed System for the Cross-Coupling of Alkenyl Methyl Ethers with Grignard Reagents under Mild Conditions.

Thomas HostierZeina NeouchyVincent FereyDomingo Gomez PardoJanine Cossy
Published in: Organic letters (2018)
A nickel-catalyzed cross-coupling of alkenyl methyl ethers with Grignard reagents, under mild conditions, is described. These conditions allowed access to various stilbenes and heterocyclic stilbenic derivatives as well as to a potential anticancer agent DMU-212.
Keyphrases
  • room temperature
  • reduced graphene oxide
  • oxide nanoparticles
  • metal organic framework
  • structure activity relationship