Promotion of NR1I3-mediated liver growth is accompanied by STAT3 activation.

Mark E MazinAndrei A YarushkinYuliya A PustylnyakElena A ProkopyevaVladimir O Pustylnyak

Published in: Molecular biology reports (2022)

This work's evidence demonstrates that NR1I3-pushed STAT3 activation contributes to TCPOBOP-induced liver growth and hepatocyte proliferation, at least in part, through its molecular targets cMyc and CyclinD1.

Keyphrases

cell proliferation
signaling pathway
high glucose
endothelial cells
stress induced